ORIGINAL RESEARCH

SELECTED PUBLICATIONS


Dr. Olga Gójska-Zygner shares her knowledge and professional experience with other veterinarians by publishing case reports (describing rare and interesting clinical cases) in Polish and international veterinary journals and review articles (presenting the current knowledge from the field of veterinary internal medicine) in Polish veterinary journals and magazines.

Hyponatraemia and syndrome of inappropriate antidiuretic hormone secretion in non-azotaemic dogs with babesiosis associated with decreased arterial blood pressure. Journal of Veterinary Research, 2019, 63(3), 339-344. DOI: 10.2478/jvetres-2019-0045

Gójska-Zygner O. Bartosik J., Górski P., Zygner W.

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) also known as Schwartz-Bartter syndrome is an endocrine disorder caused by inappropriate (increased) antidiuretic hormone secretion - arginine vasopressin. This disorder was recognized in humans during the course of various diseases including neoplastic, infectious and parasitic diseases. SIADH was also diagnosed in human malaria which is considered as a disease with similar pathogenesis to babesiosis. The results of the presented study showed development of SIADH in dogs with the early phase of babesiosis. It seems probable that SIADH which leads to hyponatremia may contribute in development of secondary hyperaldosteronism in affected dogs.

Low T3 syndrome in canine babesiosis associated with increased serum IL-6 concentration and azotaemia. Veterinary Parasitology, 2015, 211(1-2), 23-27. DOI: 10.1016/j.vetpar.2015.04.023

Zygner W., Gójska-Zygner O. , Bąska P., Długosz E.

Triiodothyronine, also known as T3, is a biologically active thyroid hormone converted from the precursor thyroxine (also known as T4). Decreased serum concentrations of T3 may be observed in many systemic diseases. This phenomenon is called low T3 syndrome, also known as euthyroid sick syndrome. It was shown in this study that increased serum interleukin 6 (IL-6; a pro-inflammatory cytokine considered one of the biomarkers of sepsis) concentration is associated with development of low T3 syndrome in dogs infected with Babesia canis. This is probably due to the cytokines action in influencing the hypothalamic-pituitary-thyroid axis and causing decreased activities among deiodinases, enzymes that convert T4 to T3.

Hyperaldosteronism and its association with hypotension and azotaemia in canine babesiosis. Veterinary Quarterly, 2015, 35(1), 37-42. DOI: 10.1080/01652176.2014.981765

Gójska-Zygner O. , Zygner W.

This work showed hyperaldosteronism in canine babesiosis, and confirmed the authors’ suppositions from two previous studies that hypokalemia, increased renal potassium excretion, and increased SUSPPUP ratio observed in dogs infected with Babesia canis results from aldosterone action, and these changes are the consequence of hypotension and decreased renal perfusion. This is the first study in the world in which the influence of the protozoan infection caused by the parasite Babesia canis on the development of secondary hyperaldosteronism in dogs was showed. The article was published in the Veterinary Quarterly (a scientific veterinary journal edited by the Taylor and Francis Group).


Increased concentration of serum TNF alpha and its correlations with arterial blood pressure and indices of renal damage in dogs infected with Babesia canis . Parasitology Research, 2014, 113(4), 1499-1503. DOI: 10.1007/s00436-014-3792-1

Zygner W., Gójska-Zygner O. , Bąska P., Długosz E.

In this study, increased serum concentrations of tumor necrosis factor (TNF) alpha (a pro-inflammatory cytokine – a secreted cell signaling protein that affects other cells) were detected in dogs infected with Babesia canis , and can partially explain the hypotension (decreased arterial blood pressure) and renal damage observed in canine babesiosis, as a consequence of causing renal ischemia and hypoxia. The article was published in the Parasitology Research (a scientific journal edited by the Springer Science+Business Media).


Prevalence of feline hyperthyroidism in mature cats in urban population in Warsaw . Bulletin of the Veterinary Institute in Pulawy, 2014, 58(2), 267-271. DOI: 10.2478/bvip-2014-0040

Gójska-Zygner O. , Lechowski R., Zygner W.

This is the first study on the prevalence of the feline hyperthyroidism in Poland. This work showed a high prevalence of hyperthyroidism in middle-age and older cats in Warsaw, and also indicated increasing age, feeding with commercial wet food, and indoor lifestyle as significant risk factors for the development of this disease in cats in Poland. This is the first work from Poland in which prevalence and risk factors of feline hyperthyroidism were studied. The article was published in the Bulletin of the Veterinary Institute in Pulawy (a scientific veterinary journal edited by the National Veterinary Research Institute in Pulawy).


Changes in the SUSPPUP ratio and fractional excretion of strong monovalent electrolytes in hospitalized dogs with canine babesiosis . Polish Journal of Veterinary Sciences, 2012, 15(4), 791-792. DOI: 10.2478/v10181-012-0119-y

Zygner W., Gójska-Zygner O. , Wędrychowicz H.

This work showed increased renal excretion of sodium, potassium and SUSPPUP ratio (an index to assess the extent of mineralocorticoid excess) in dogs with babesiosis. These results were indicative for acute tubular necrosis and aldosterone excess in canine babesiosis. The article was published in the Polish Journal of Veterinary Sciences (a scientific veterinary journal edited by the Polish Academy of Sciences Committee of Veterinary Sciences).


Strong monovalent electrolyte imbalances in serum of dogs infected with Babesia canis . Ticks and Tick-borne Diseases, 2012, 3(2), 107-113. DOI: 10.1016/j.ttbdis.2012.02.002

Zygner W., Gójska-Zygner O. , Wędrychowicz H.

This study showed hyponatremia (decreased serum sodium concentration), hypokalemia (decreased serum potassium concentration), and hyperchloremia (increased serum chloride concentration) in dogs infected with Babesia canis . The authors of this work speculated that the observed pathological changes in electrolyte concentrations resulted from hypotension, acid-base disturbances and endocrine disorders caused by aldosterone and antidiuretic hormone action. The article was published in the Ticks and Tick-borne Diseases (a scientific journal edited by the Elsevier, an academic publishing company).

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