Dr. Olga Gójska-Zygner shares her knowledge and professional experience with other veterinarians by publishing case reports (describing rare and interesting clinical cases) in Polish and international veterinary journals and review articles (presenting the current knowledge from the field of veterinary internal medicine) in Polish veterinary journals and magazines.
Serum SDMA determination in early diagnosis of kidney diseases in feline hyperthyroidism - a case report. Magazyn Weterynaryjny, 2018, wydanie specjalne nr 1, 112-115 [IN POLISH]
Lechowski R., Gójska-Zygner O., Wojtkowska A., Zabielska-Koczywąs K.
The case report presents an elderly cat with hyperthyroidism and early stage of chronic kidney disease which was recognized using serum SDMA (symmetric dimethylarganine) determination, which is kidney function biomarker (more sensitive than serum creatinine). In this case early detection of chronic kidney disease allowed to begin treatment of the cat with telmisartan (angiotensin II receptor AT1 antagonist). This led to decrease of serum urea and SDMA concentration, and then stable state of the cat enabled surgical treatment of hyperthyroidism. However, the owner of the cat did not agree eventually for surgical therapy.
Progressing generalized muscular weakness and acute blindness in a 15-year old cat – case report of primary hyperaldosteronism. Magazyn Weterynaryjny, 2014, 23(211), 1235-1238. [in Polish]
Gójska-Zygner O. , Łobaczewska O., Marciński P.
In this article the authors presented the case of an older cat with clinical findings such as hypokalemia (decreased serum potassium concentration), increased basic serum aldosterone concentration, hypertension (increased arterial blood pressure), presence of a hypoechoic structure adhesive to the left adrenal gland, and bilateral retinal detachment. These observations were typical for primary hyperaldosteronism, the disease (also called Conn’s syndrome) resulted from overproduction of aldosterone by a functioning adrenal tumor.
Cutaneous paraneoplastic syndrome in a cat with thymoma. Tierärztliche Praxis Kleintiere, 2013, 41(4), 255-259.
Gójska-Zygner O. , Karaś-Tęcza J., Lechowski R., Rodo A., Dolka I.
A rare case of an older cat with exfoliative dermatitis (generalized scaly dermatitis) caused by a tumor of the thymus is reported in this case description. Histopathological examination confirmed thymoma (a tumor developing from epithelial cells of the thymus) as a cause of the skin disease in this cat. Dermatologic signs were clinical signs of paraneoplastic syndrome (pathological changes associated with a neoplastic disease but distant from the tumor) in this case.
Conservative treatment of Conn’s syndrome in a dog. Weterynaria w Praktyce, 2013, 10(6), 74-78. [in Polish]
Gójska-Zygner O. , Marciński P.
A case of an 8-year old neutered female dog with Conn’s syndrome (primary hyperaldosteronism) conservatively treated for a period of over five months has been reported in this article. The owner of this dog did not agree to surgical treatment (adrenalectomy – surgical removal of the adrenal gland) owing to his financial conditions. During this period (over five months), treatment with amlodipine and spironolactone did not cause any adverse effects.
Incontinence and plantigrade posture as leading symptoms of hydrocephalus in 5-month-old Burmese cat. A case report. Medycyna Weterynaryjna, 2012, 68(8), 504-509. [in Polish]
Gójska-Zygner O. , Galanty M., Lechowski R., Olkowski A.
In this article the authors presented a case of a young cat with acquired hydrocephalus with incontinence and plantigrade posture as leading clinical signs. Hydrocephalus in this cat was diagnosed using magnetic resonance imaging (MRI) technique, and surgical treatment was intended. Unfortunately, pathological changes detected using MRI and cerebrospinal fluid analysis were highly suggestive for an infective cause of the hydrocephalus (dry form of feline infectious peritonitis (FIP) seemed to be the most probable cause), and owing to this fact the decision to perform euthanasia was made by the owner of the cat.
Functioning unilateral adrenocortical carcinoma in a dog. Canadian Veterinary Journal, 2012, 53(6), 623-625.
Gójska-Zygner O. , Lechowski R., Zygner W.
A case of an older intact female dog with clinical signs typical for primary hyperaldosteronism (including adrenal tumor) but with surprisingly low levels of serum aldosterone (both baseline and ACTH-stimulated), and a complete ceasing of all clinical signs after surgical treatment (unilateral adrenalectomy) is reported in this article. Histopathological examination of the removed adrenal gland revealed adrenal cortical carcinoma. The authors of this report hypothesized overproduction of the precursor for aldosterone (deoxycorticosterone) by the endocrinologically active adrenal tumor in this dog as a cause of clinical signs typical for mineralocorticoid excess.
This work was included to the list of “ "Top Endocrine Publications 2012: The Canine Adrenal Gland" in the blog of the world-renowned veterinary endocrinologist Dr. Mark E. Peterson from the Animal Endocrine Clinic in New York City “Insights into veterinary endocrinology by Dr. Mark E. Peterson”.
Hyperthyroidism masked by euthyroid sick syndrome in leukemic cat – a case study . Życie Weterynaryjne, 2012, 87(1), 43-46. [in Polish]
Gójska-Zygner O. , Lechowski R., Rodo A., Winnicka A.
In this case report the authors presented the history of a middle-aged cat with hyperthyroidism and acute lymphoblastic leukemia. The combination of these two diseases meant that the increase of serum thyroxine concentration was very mild (within non-diagnostic interval) and diagnosis of hyperthyroidism was difficult. Further diagnostic tests, however, were not performed owing to the owner’s decision to euthanize. Post mortem histopathological examination of the thyroid gland showed hyperplastic changes typical for feline hyperthyroidism.
Canine iatrogenic persistent hypoadrenocorticism after short-term treatment of hyperadrenocorticism with trilostane – a case report. Veterinarski Arhiv, 2011, 81(5), 699-705.
Gójska-Zygner O. , Lechowski R., Zygner W.
A case of persistent hypoadrenocorticism (16 months reported) after short-term (13 days) treatment of hyperadrenocorticism with trilostane (adrenal steroid synthesis inhibitor) in a middle-aged dog is reported in this case description. The authors of this report hypothesized adrenal necrosis (probably due to an idiosyncratic drug reaction – dose independent, rare and unpredictable) which has been rarely reported in dogs after short-term treatment with trilostane.
Vincristine and cyclophosphamide in the treatment of persistent anemia and thrombocytopenia related to Babesia canis infection in a dog. Życie Weterynaryjne, 2011, 86(5), 374-378. [in Polish]
Zygner W., Gójska-Zygner O. , Szmidt K.
In this article a case of a dog with immune-mediated hemolytic anemia and thrombocytopenia after infection with Babesia canis (intra-erythrocytic protozoan parasite) progressing despite glucocorticoid therapy is presented. In this case initial treatment with vincristine and prednisolone, and further therapy with cyclophosphamide led to complete recovery from immune-mediated hemolytic anemia.
Disease and sudden death case study: A 16-year-old retriever. Veterinary Times, 2010, 40(31) August 9, 20-24.
Gójska-Zygner O. , Zygner W.
A case of an older dog with unilateral epistaxis (bleeding from the nose), polyclonal gammopathy, anemia, and systemic inflammatory response syndrome that suddenly died after a short course of the disease is reported. The authors hypothesized sepsis as a cause of death, however, an etiological agent was not identified.
Azithromycin in the treatment of a dog infected with Giardia intestinalis. Polish Journal of Veterinary Sciences, 2008, 11(3), 231-234.
Zygner W., Jaros D., Gójska-Zygner O. , Wędrychowicz H.
In this case report the authors presented the history of a dog infected with a Giardia intestinalis (protozoan parasite causing diarrhea) strain presumptively fenbendazole- and metronidazole-resistant that was successfully treated with azithromycin (macrolide antibiotic) as an experimental therapy. This work showed another additional option for the treatment of dogs infected with Giardia intestinalis .